NFL Super Bowl odds 2022: Model shares predictions, picks to win, teams to avoid

The Kansas City Chiefs, led by quarterback Patrick Mahomes, are the favorites in the latest 2022 Super Bowl odds at +525. Not far behind are the reigning Super Bowl champion Tampa Bay Buccaneers, as they look to defend their title with +650 Super Bowl 56 odds to repeat. A trio of teams, the Los Angeles Rams, San Francisco 49ers and Baltimore Ravens, have NFL odds of +1400, though the Buffalo Bills are sitting the No. 3 spot at +1300 following a breakout campaign from quarterback Josh Allen and wide receiver Stefon Diggs.