Reds vs. Cubs odds, line: 2021 MLB picks, predictions for May 28 from proven computer model

The Chicago Cubs will try to continue their push for the lead in the NL Central when they host the Cincinnati Reds in the first game of a three-game series on Friday afternoon at Wrigley Field in Chicago. The Cubs (27-22) have won four in a row and have pulled within a half-game of division-leading St. Louis. Meanwhile, the Reds (22-26) sit in fourth place in the division and trail the Cardinals by five games. On Friday, Chicago's Adbert Alzolay (2-4, 4.30 ERA) faces Vladimir Gutierrez, who will be making his major league debut.