NFL Super Bowl odds 2022: Model gives predictions, picks to win, teams to avoid

One look at the 2022 Super Bowl odds from sportsbooks like William Hill tells you quarterback is king, which is why Patrick Mahomes and the Kansas City Chiefs are the betting favorites at +525 despite losing to Tampa Bay in February. Quarterback Tom Brady will turn 44 in August, but after knocking off Kansas City to win his seventh Super Bowl ring in his first season with the Buccaneers, it's no surprise that the Bucs are the second favorite at +650 in the current Super Bowl odds 2022.